The CDC Classification System for HIV Infection is a medical classification system used by the US Centers for Disease Control and Prevention (CDC) to classify HIV disease and infection. This system is used to allow the government to handle epidemic statistics and determine who is receiving US government assistance.
Video CDC classification system for HIV infection
In adults and teenagers
This classification system is how the United States agency, the Centers for Disease Control and Prevention (CDC) classifies HIV disease and infections. This is to enable the government to handle epidemic statistics and determine who is receiving US government assistance. In 1993, the CDC added pulmonary tuberculosis, recurrent pneumonia, and invasive cervical cancer to a list of clinical conditions in the definition of AIDS surveillance cases published in 1987 and expanded the definition of AIDS surveillance cases to include all HIV-infected people with less T-lymphocyte CD4 T-cell counts of 200 cells/uL or a CD4 percentage of less than 14. Sufficient variation exists in the relative risk of death after a different AIDS-defining clinical condition.
According to the US CDC definition, a person has AIDS if he is infected with HIV and comes with one of the following:
- T-cell CD4 counts below 200 cells/Âμl (or T4 lymphocyte total percentage less than 14%)
OR
- he has one of the following defining diseases:
- Bronchial, tracheal, or lung candidiasis
- Esophageal candidiasis
- Cervical cancer (invasive)
- Coccidioidomycosis, disseminated or extrapulmonary
- Cryptococcosis, extrapulmonary
- Cryptosporidiosis, chronic intestine more than 1 month
- Cytomegalovirus Disease (other than liver, spleen or lymph node)
- Encephalopathy (HIV-related)
- Herpes simplex: chronic ulcer (for more than 1 month); or bronchitis, pneumonitis, or esophagitis
- Histoplasmosis, disseminated or extrapulmonary
- Isosporiasis, chronic intestine (for more than 1 month)
- Kaposi's sarcoma
- Brain of Lymphoma Burkitt, immunoblastic or main brain
- Mycobacterium avium complex
- Mycobacterium, another species, disseminated or extrapulmonary
- Pneumocystis carinii pneumonia
- Pneumonia (recurring)
- Progressive multifocal leukoencephalopathy
- Septicemia Salmonella (relapse)
- Toxoplasmosis of the brain
- Tuberculosis
- Waste syndrome due to HIV
People who are not HIV-infected can also develop this condition; this does not mean they have AIDS. However, when a person presents laboratory evidence against HIV infection, the AIDS diagnosis is ruled out unless the patient has:
- underwent high-dose corticoid therapy or other immunosuppressive/cytotoxic therapy within three months prior to the onset of indicator disease
- OR has been diagnosed with Hodgkin's disease, non-Hodgkin's lymphoma, lymphocytic leukemia, multiple myeloma, or lymphoreticular or histiocytic tissue, or angioimmunoblastic lymphoadenopathy
- OR unusual genetic immunodeficiency syndrome from HIV infection, such as those involving hypogamma globulinemia
AND
- individuals already have Pneumocystis carinii pneumonia
- OR one of the defining diseases above AND a T-cell CD4 cell count below 200 cells/Âμl (or a percentage of total CD4 T-cell lymphocytes less than 14%).
Maps CDC classification system for HIV infection
In children
Due to additional knowledge of HIV disease progression among children, a revised classification system for HIV infection in children was developed in 1994 that replaced the pediatric HIV classification system published in 1987. A child for the CDC goal was individuals less than 13 year. Standard anti-HIV IgG antibody tests can not be used to reliably demonstrate the infant's status before the age of 18 months, so viral antigen testing is used.
In the new system, HIV-infected children are classified into mutually exclusive categories based on three parameters:
- a) infection status
- b) clinical status
- c) immunological status
This classification system reflects the stage of childhood illness, establishes an exclusive classification category, and balances the simplicity and medical accuracy of the classification process. This document also explains the revised pediatric definition for the two conditions of acquired immunodeficiency deficiency.
When a baby is born to an HIV-infected mother, the diagnosis of HIV infection is complicated by the presence of maternal anti-HIV IgG antibody, which crosses the placenta into the fetus. Indeed, almost all children born to HIV-infected mothers are HIV-positive antibodies at birth, although only 15% -30% are actually infected.
Category N: Asymptomatic
Children who have no signs or symptoms are considered as a result of HIV infection or who have only one of the conditions listed in Category A.
Category A: Symptomatic
Children with two or more of the conditions listed below but no conditions listed in Category B and C.
- Lymphadenopathy (& gt; = 0.5 cm in more than two sites; bilateral = one site)
- Hepatomegaly
- Splenomegaly
- Dermatitis
- Parotitis
- Recurrent or persistent upper respiratory tract infections, sinusitis, or otitis media
Category B: Symptomatic enough
References
Source of the article : Wikipedia
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