Magnesium sulfate as a drug is used to treat and prevent magnesium and low blood spasms in women with eclampsia. It is also used in the treatment of torsades de pointes, severe exacerbations of asthma, constipation, and barium poisoning. This is given by injection into blood vessels or muscles as well as through the mouth. As epsom salts, it is also used for mineral baths.
Common side effects include low blood pressure, reddened skin, and low blood calcium. Other side effects may include vomiting, muscle weakness, and decreased breathing. Although there is evidence that use during pregnancy may harm the baby, the benefits under certain conditions outweigh the risks. Its use during breastfeeding is considered safe. Magnesium sulfate for medical purposes is magnesium sulfate heptahydrate salt. The way it works is not fully understood, but it is believed to involve suppressing the action of neurons.
Magnesium sulphate began to be used medically since at least 1618. It is in the List of Essential Medicines of the World Health Organization, the most effective and safe medicines needed in the health system. The cost of wholesale in developing countries is about 0.35 to 8.73 USD per 10 ml of 50% solution. In the UK, 4 ml of 20% solution of NHS costs about 10.23 pounds. In the United States, treatment programs typically cost less than 25 USD.
Video Magnesium sulfate (medical use)
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Eclampsia
Magnesium sulfate is the main treatment and preventive measure in women with eclampsia. It lowers systolic blood pressure while maintaining diastolic blood pressure, thus leaving the blood flow to the fetus uncompromising.
Initial delivery
Magnesium sulfate was once used as tocolytics, but meta-analysis failed to support it as an anti-contraction drug. Long-term use (more than five to seven days) can cause health problems for the baby.
In those at risk for preliminary labor, magnesium sulfate appears to reduce the risk of cerebral palsy. It is unclear whether it helps those born in the long run. Guidelines for the use of magnesium sulfate in mothers at risk for preterm labor are not followed.
Bath salt
Magnesium sulphate is used in bath salts, especially in flotation therapy, where high concentrations increase the specific gravity of the bath water, effectively making the body lighter. Traditionally, it is also used to prepare foot baths, which are intended to relieve leg pain. Reasons to include some cosmetic salts: increased ionic strength prevents some temporary skin wrinkling (partial maceration) caused by prolonged limb immersion in pure water. Magnesium and sulphate ions are naturally present in some mineral waters. The claimed health benefits of Epsom salt baths have not been proven.
Paste
Magnesium sulphate paste is also available which is claimed to be useful for small boils or local infections. The composition of British Pharmacopoeia standard dried Magnesium Sulfate 47.76% w/w, Phenol 0.49% w/w. and glycerol (E422).
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Research
Magnesium sulfate has been used as an experimental treatment of Irukandji syndrome caused by envenomation by certain Irukandji jellyfish species, but the efficacy of this treatment remains unproven.
See also
- Magnesium (medical use)
References
Source of the article : Wikipedia
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